Vasodilator Therapy: Nitrates and Nicorandil
نویسندگان
چکیده
منابع مشابه
Nicorandil as a hybrid between nitrates and potassium channel activators.
Nicorandil, although structurally a nitrate, differs from classic nitrates in several respects. It preferentially dilates resistive vessels. Its effect on venous return in dogs is not unanimously a decrease but rather an increase. In high doses or concentrations it suppresses myocardial contraction and ventricular automaticity, nearly sparing sinoatrial nodal automaticity and atrioventricular n...
متن کاملVasodilator therapy of dilated cardiomyopathy.
Vasoconstriction increases impedance to ventricular ejection and impairs the performance of the dilated myopathic heart. Vasodilator drug therapy by reducing vascular resistance, increasing vascular compliance and increasing vascular capacitance improves cardiac function and relieves the signs and symptoms of congestive heart failure. Earlier intervention in an attempt to alter the natural hist...
متن کاملSide effects of vasodilator therapy.
Vasodilating antihypertensive drugs have in common the capacity to activate the peripheral sympathetic nervous system through the carotid sinus baroreceptor reflex mechanism, thereby increasing heart rate, renin release, and sodium and water retention. They differ in their tendencies to augment cardiac output and to relieve or precipitate cardiac failure and arrhythmias. Vasodilating antihypert...
متن کاملCerebral vasodilator therapy in stroke.
Cerebral Vasodilator Therapy in Stroke • Cerebral vasodilating agents have been questioned as an effective form of therapy for the stroke patient and even have been considered by some to be harmful. Animal studies show that often vasodilating agents will cause an intracerebral steal, but such a reaction has rarely been demonstrated in stroke patients. Several studies measuring cerebral blood fl...
متن کاملVASODILATOR THERAPY FOR CHF/Walsh and Greenberg
20. Weber KT, Janicki JS, Reeves RC, Hefner LL, Reeves TJ: Determinants of stroke volume in the isolated canine heart. J Appl Physiol 37: 742, 1974 21. Beneken JEW, Guyton AC, Sagawa K: Coronary perfusion pressure and left ventricular function. Pfluegers Arch 305: 76, 1969 22. Abel FL: Fourier analysis of left ventricular performance: evaluation of impedance matching. Circ Res 28: 119, 1971 23....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cardiovascular Drugs and Therapy
سال: 2016
ISSN: 0920-3206,1573-7241
DOI: 10.1007/s10557-016-6668-z